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Interestingly, both of pro-HGF and cleaved HGF can bind to c-MET with high affinity, but only cleaved HGF can activate c-MET signaling, indicating that proteolytic cleavage is critical for HGF-induced c-MET activation 9,10

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Areas of Ongoing Research Interest Published studies and laboratory investigations have explored GHK-Cu in relation to: Peptide signaling pathways in cell cultures Copper transport and regulation models Gene expression markers in laboratory settings Extracellular matrix structure research Cellular response mechanisms under controlled conditions It is important to note that these research areas are experimental and are conducted exclusively in laboratory environments